What are they?

• “Poly” = long chains. “Nucleotides” = building blocks of DNA.

• Highly purified DNA derived from salmon/trout -high purification makes them very safe to use.

• At Dr Smith Aesthetics - we use Plinest polynucleotides by Mastelli - Used for many years in regenerative medicine with lots of scientific research behind it.

 

What do they do?

• Target your own skin cells called fibroblasts to promote skin rejuvenation from within.

• Fibroblasts are responsible for producing collagen and elastin - essential for skin structure, framework, wound healing and overall skin health. The more we age, the less efficient our fibroblast cells are - leading to the less desired effects of ageing.

• Help regulate skin cells called melanocytes to help control pigmentation and help with uneven skin tone - dark pigmentation or dark circles under eyes.

• Overall skin health and healing - good for scars and inflammatory skin conditions such as rosacea or eczema. Give a healthy, glowing appearance.

 

Where can they be used?

• Pretty much anywhere! 

 

What concerns do they target?

• Fine lines and wrinkles - increase skin structural support with increasing your own collagen, elastin and hyaluronic acid production.

• Improve overall skin health and glow.

• Under eye lines or puffiness - help to tighten the under eye area.

• Dark eye circles - dark circles can be due to multiple factors, such as - hollowing, thin skin, pigmentation. Polynucleotides can improve all of these.

• Hair loss - improved the skin environment to help stimulate hair growth as well as thicken current hair - Great in combination with other treatments such as PRP.

 

How is it given?

• Numbing cream is used to cover the target area to help numb the skin.

• Multiple, small, superficial injections in the target area with a small needle (mesotherapy), resulting in small “blebs” under the skin.

• Can also be given via a dermal cannula under the skin - less precise but covers a wide area with only a few injection sites.

 

 

What is the downtime/recovery?

• Mesotherapy/small bleb technique - Small blebs can last a number of hours.

• Cannula technique is better if have important events the next few days.

• Possibility of having minor swelling and bruising for a few days.

• Discuss which option is best with the practitioner if having a a big event a few days post treatment.

• Highly purified so very safe.

• Can have alongside other treatments such as anti-wrinkle injections, dermal fillers, PRP and skin boosters.

 

Treatment course:

• Recommended treatment course; 3x treatments of the target area 2-4 weeks apart, followed by a 1x maintenance every 6-12 months.

• Note scalp polynucleotide recommended course: 4x treatments, spaced 1-2 weeks apart, followed by 4x treatments every 3 weeks apart.

 

Results

• As they work at a cellular level, results are gradual, rather than a quick fix - can see results after 1st or 2nd treatment.

• Great for patients who want a more natural approach rather than anti-wrinkle injections or fillers.

• Work great with other treatments or alone.

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